Advancing Nutritional Neuroscience

At Northumbria University, Newcastle upon Tyne, UK.

Brain Health Food to Benefit Cognitive Functions
Healthy food for brain and memory.

About Us

Based at Northumbria University, Newcastle upon Tyne, UK, our research investigates the impact of nutrients, extracts and whole foods on brain function and psychological health and well-being. A key question of our work asks how can diet and nutrition support optimal brain health across the lifespan.

Our Capabilities

Our lab facilities were purpose-built for the testing of nutritional interventions in humans and we do so in accordance with good clinical practice (GCP) guidelines. Our 4 large testing labs contain individual testing desks which are divided to allow visual isolation from other participants.

Cognitive testing via COMPASS

The Computerised Mental Performance Assessment System (COMPASS) is a user-friendly platform for delivering cognitive tasks. See further details about the system below.

Near-infrared spectroscopy (NIRS)

Indirect calorimetry

Trans-cranial doppler sonography (TCD)

NIRS is a non-invasive neuroimaging technique, using infrared light to monitor cerebral blood flow. We have 2 NIRS systems: Continuous wave and frequency domain 'quantitative' NIRS.

Oxygen uptake and carbon dioxide production can be measured from expired pulmonary air using our on-line gas analysis system and this data used to calculate total energy expenditure, fat and carbohydrate metabolism.

TCD is a non-invasive method of measuring cerebral blood flow velocity from the basal intra-cerebral vessels through the intact skull. TCD can be combined with other neuroimaging devices such as NIRS.



Nutrition Trials at Northumbria (NUTRAN)

NUTRAN brings together world leading expertise and state of the art facilities across six labs within Northumbria University. As part of this multidisciplinary research group, our lab collaborates with colleagues across the university to conduct ambitious research trials which address global challenges and the needs of our industry partners.

This integrated service allows us to create bespoke research trials to address each unique challenge; drawing on the expertise from the appropriate labs to do so.


COMPASS

Our key area of expertise is assessing the effects of nutritional supplements on cognitive function in humans; from children through to older adults. We do this using our own task delivery system COMPASS.

COMPASS currently comprises over 20 cognitive tasks; many based on traditional assessments, which measure attention, vigilance, working-, spatial- and secondary memory, executive function, mood and tasks which induce cognitive demand. COMPASS tasks have been well validated, with hundreds of published journal articles evidencing their sensitivity to a range of nutritional interventions.


Drop Shadow

Cognimapp

A smart-phone cognitive and mood assessment application, which allows participants to complete assessments outside of the laboratory during nutritional supplementation period.

Our excellent facilities and resources are designed to meet the high demands required for fully auditable controlled-trial research.

Our Team

Director

david.kennedy@northumbria.ac.uk

Associate Director

philippa.jackson@northumbria.ac.uk

Nutrition Trials at Northumbria (NUTRAN) Director

emma.l.wightman@northumbria.ac.uk

Research Fellow

f.dodd@northumbria.ac.uk

Senior Research Assistant

jo.forster@northumbria.ac.uk

Senior Research Assistant

ellen.f.smith@northumbria.ac.uk

Research Assistant

jessica.p.greener@northumbria.ac.uk

Research Assistant

a.small@northumbria.ac.uk

Research Assistant

rian.e.elcoate@northumbria.ac.uk

Research Assistant

emily2.haworth@northumbria.ac.uk

Research Assistant

charlotte2.kenney@northumbria.ac.uk

Abi Harrop

Research Assistant

a.harrop@northumbria.ac.uk

Isa Bashir

Research Assistant

i.bashir@northumbria.ac.uk

Holly Lancaster

Research Assistant

holly2.lancaster@northumbria.ac.uk

Affiliates

Professor

crystal.haskell-ramsay@northumbria.ac.uk

Professor

darren.smith@northumbria.ac.uk

Studies currently recruiting

We have the following exciting research participation opportunities available:

Lemon Verbena Study

WHO?

Children and adolescents aged 8-17 years

who exert hyperactive-impulsive behaviours but do not have a diagnosis of ADHD.

WHY?

To investigate the effects of lemon verbena extract on behaviour, mood & cognitive performance.

WHAT WILL I NEED TO DO?

Your child will need to attend a virtual screening session, followed by four sessions in our Newcastle City Centre lab.

Your child will receive £120 in vouchers.

This study has been approved by the University Ethical Approval System (49191) at Northumbria University.

GET IN TOUCH

Stress Study

WHO?

Adults aged 30-50 years

WHY?

To investigate the effects of kanna flower extract on response to stress, mood & cognitive performance.

WHAT WILL I NEED TO DO?

You will need to attend a virtual screening session, followed by three sessions in our Newcastle City Centre lab.

You will receive £160 upon completion of the study.

This study has been approved by the University Ethical Approval System (40934) at Northumbria University.

GET IN TOUCH

Sage 3 Study

WHO?

Adults aged 18-45 years

WHY?

To investigate the effects of sage extract, fruit polyphenols and caffeine on cognitive function and mood.

WHAT WILL I NEED TO DO?

You will need to attend a virtual screening session, followed by four

sessions in our Newcastle City Centre lab.

You will receive £280 upon completion of the study.

This study has been approved by the University Ethical Approval System (52916) at Northumbria University.

GET IN TOUCH

If you are not eligible or able to take part in any of these current studies please be advised we will have other studies in the near future.

To make sure you are kept up to date about new projects you can sign up to our participant database and we will contact you when new studies start. Use the link below to sign up.


Sign up to the participant database


We store all information in accordance with GDPR regulations and will remove your details, at any time, upon request. We will only use the information you provide to contact you about Northumbria University research studies and will not pass on these details to any third party organisations.




Publications

The BPNRC has an extensive publication history, encompassing the last 20 years.


Micronutrients

Kennedy DO, Stevenson EJ, Jackson PA, Dunn S, Wishart K, Bieri G, Barella L, Carne A, Dodd FL, Robertson BC, Forster J, Haskell-Ramsay CF (2016) Multivitamins and minerals modulate whole-body energy metabolism and cerebral blood-flow during cognitive task performance: a double-blind, randomised, placebo-controlled trial. Nutr Metab 13:11


Haskell CF, Kennedy DO (2013) Vitamins, Cognition, and Mood in Healthy Nonelderly Adults. In Scholey AB (Ed) Advances in Natural Medicines, Nutraceuticals and Neurocognition. Taylor Francis, pp 105-136


Kennedy DO, Veasey R, Watson A, Dodd F, Jones E, Tiplady B, Haskell CF (2011) Vitamins and psychological functioning: a mobile phone assessment of the effects of a B vitamin complex, vitamin C and minerals on cognitive performance and subjective mood and energy. Human Psychopharmacology: Clinical and Experimental 26:338-47


Kennedy DO, Jones E, Haskell CF (2011) Vitamin status, cognition and mood in cognitively intact adults. In Benton D (Ed) Lifetime nutritional influences on cognition, behaviour and psychiatric illness. Woodhead publishing, pp 194-250


Kennedy DO and Haskell CF (2011) Vitamins and Cognition: What is the Evidence? Drugs 71(15):1957-71

Haskell CF, Robertson BC, Jones E, Forster J, Jones R, Wilde A, Maggini S, Kennedy DO (2010) Effects of a multi-vitamin/mineral supplement on cognitive function and fatigue during extended multi-tasking. Human Psychopharmacology 25:448-61


Kennedy DO, Veasey R, Watson A, Dodd F, Jones E, Maggini S, Haskell CF (2010) Effects of high-dose B vitamin complex with vitamin C and minerals on subjective mood and performance in healthy males. Psychopharmacology 211:55-68


Kennedy DO, Haskell CF, Robertson B, Reay J, Brewster-Maund C, Luedemann J, Maggini S, Ruf M, Zangara A, Scholey AB (2008) Improved cognitive performance and mental fatigue following a multi-vitamin and mineral supplement with added guarana (Paullinia cupana). Appetite 50:506-13


Haskell CF, Scholey AB, Jackson PA, Elliott JM, Defeyter MA, Greer J, Robertson BC, Buchanan T, Tiplady B, Kennedy DO (2008) Cognitive and mood effects in healthy children during 12 weeks supplementation with multi-vitamin/minerals. British Journal of Nutrition 100:1086-1096



Herbs

Wightman EL, Jackson, PA, Spittlehouse B, Heffernan T, Guillemet D & Kennedy DO (2021). The Acute and Chronic Cognitive Effects of a Sage Extract: A Randomized, Placebo Controlled Study in Healthy Humans. Nutrients, 13(1), 218.


Kennedy DO, Okello E, Chazot P, Howes M-J, Ohiomokhare S, Jackson PA, Haskell-Ramsay C, Khan J, Forster J, Wightman E (2018). Volatile terpenes and brain function: Investigation of the cognitive and mood effects of Mentha × piperita L. essential oil with in vitro properties relevant to central nervous system function. Nutrients 10 (8) 1029.


Kennedy DO & Wightman EL (2011) Herbal extracts and phytochemicals: plant secondary metabolites and the enhancement of human brain function. Advances in Nutrition 2:32-50


Kennedy D, Dodd F, Robertson B, Okello E, Reay J, Scholey A, Haskell C (2011) Monoterpenoid extract of sage (Salvia lavandulaefolia) with cholinesterase inhibiting properties improves cognitive performance and mood in healthy adults. Journal of Psychopharmacology 25:1088-1100


Reay JL, Scholey AB, Kennedy DO (2010) Panax ginseng (G115) improves aspects of working memory performance and subjective ratings of calmness in healthy young adults. Human Psychopharmacology-Clinical and Experimental;25:462-471


Kennedy DO (2009) Herbs affecting the Central Nervous System. In (Eds) Mukherjee PK, Houghton PJ. Evaluation of Herbal Medicinal Products – Perspectives of Quality, Safety and Efficacy, Pharmaceutical Press, Royal Pharmaceutical Society of Great Britain, London, UK


Reay JL, Scholey AB, Milne A, Fenwick J, Kennedy DO (2008) Panax ginseng has no effect on indices of glucose regulation following acute or chronic ingestion in healthy volunteers. British Journal of Nutrition 101:1673-1678


Scholey AB, Tildesley NTJ, Ballard CG, Wesnes KA, Tasker A, Perry EK, Kennedy DO (2008) An extract of Salvia (sage) with anticholinesterase properties improves memory and attention in healthy older volunteers. Psychopharmacology 198:127-139


Kennedy DO, Jackson PA, Haskell CF, Scholey AB (2007) Modulation of cognitive performance following single doses of 120mg Ginkgo biloba extract administered to healthy young volunteers. Human Psychopharmacology 22:559-66






Kennedy DO, Reay JL, Scholey AB (2007) Effects of 8 weeks administration of Korean Panax ginseng extract on the mood and cognitive performance of healthy individuals. Journal of Ginseng Research 31(1):34-43


Kennedy DO, Haskell CF, Mauri PL, Scholey AB (2007) Acute cognitive effects of standardised Ginkgo biloba extract complexed with phosphatidylserine. Human Psychopharmacology – Clinical and Experimental. 22(4):199-210



Kennedy DO, Little W, Haskell CF, Scholey AB (2006) Anxiolytic effects of a combination of Melissa officinalis and Valeriana officinalis during laboratory induced stress. Phytotherapy Research 20:96-102


Kennedy DO, Pace S, Haskell C, Okello EJ, Milne A, Scholey AB (2006) Effects of cholinesterase inhibiting sage (Salvia officinalis) on mood, anxiety and performance on a psychological stressor battery. Neuropsychopharmacology 31(4):845-52


Reay JL, Kennedy DO, Scholey AB (2006) Effects of Panax ginseng, consumed with and without glucose, on blood glucose levels and cognitive performance during sustained ‘mentally demanding’ tasks. Journal of Psychopharmacology 20(6):771-781


Reay JL, Kennedy DO, Scholey AB (2006) The glycaemic effect of single doses of Panax ginseng (G115) in young healthy volunteers. British Journal of Nutrition 96:639-642


Kennedy DO, Reay JL, Scholey AB (2006) Effects of 8 weeks administration of Korean Panax ginseng extract on mood and cognitive performance in healthy individuals. In: Oh S, Choi T (Eds) Advances in Ginseng Research 2006. Korean Society of Ginseng. Seoul. Korea


Kennedy DO and Scholey AB (2006) The psychopharmacology of European herbs with cognition enhancing properties. Current Pharmaceutical Design. 12(35):4613-4623


Scholey A, Kennedy D, Wesnes K (2005) The psychopharmacology of herbal extracts: issues and challenges. Psychopharmacology 179(3):705-707


Tildesley NTJ, Kennedy DO, Perry EK, C.G. Ballard CG, Wesnes KA, Scholey AB (2005) Positive modulation of mood and cognitive performance following administration of acute doses of Salvia lavandulaefolia essential oil to healthy young volunteers. Physiology and Behavior 83:699-709


Reay JL, Kennedy DO, Scholey AB (2005) Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity. Journal of Psychopharmacology 19(4):357-365


Kennedy DO, Little W, Scholey AB (2004) Attenuation of laboratory induced stress in humans following acute administration of Melissa officinalis (Lemon Balm). Psychosomatic Medicine 66:607-613


Tildesley NTJ, Kennedy DO, Perry EK, Ballard C, Savelev S, Wesnes KA, Scholey AB (2003) Salvia lavandulaefolia (Spanish Sage) enhances memory in healthy young volunteers. Pharmacology, Biochemistry and Behavior 75:669-674


Kennedy DO, Scholey AB, Drewery L, Marsh VR, Moore B, Ashton H (2003) Electroencephalograph (EEG) effects of single doses of Ginkgo biloba and Panax ginseng in healthy young volunteers. Pharmacology, Biochemistry and Behavior 75(3):701-709


Kennedy DO, Wake G, Savealev S, Tildesley NTJ, Perry EK, Wesnes KA, Scholey AB (2003) Modulation of mood and cognitive performance following administration of single doses of Melissa officinalis (Lemon balm) with human CNS nicotinic and muscarinic receptor binding properties. Neuropsychopharmacology 28:1871-1881


Kennedy DO and Scholey AB (2003) Ginseng: potential in the enhancement of cognitive performance and mood. Pharmacology, Biochemistry and Behavior 75:687-700


Kennedy DO, Scholey AB and Wesnes KA (2002) Modulation of cognition and mood following administration of single doses of Ginkgo biloba, Ginseng and a Ginkgo/Ginseng combination to healthy young adults. Physiology and Behavior 75:739-751


Kennedy DO, Scholey AB, Tildesley NTJ, Perry EK, and Wesnes KA (2002) Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (Lemon Balm). Pharmacology, Biochemistry and Behavior 72:953-964


Scholey AB and Kennedy DO (2002) Acute, dose-dependent cognitive effects of Ginkgo biloba, Panax Ginseng and their combination in healthy young volunteers: differential interactions with cognitive demand. Human Psychopharmacology – Clinical and Experimental 17:35-44


Kennedy DO (2002) The effects of Ginseng on memory and mood. In Nam-In Baek (Ed) Advances in Ginseng Research 2002. The Korean Society of Ginseng. Seoul. Korea


Kennedy DO, Scholey AB and Wesnes K (2001) Differential, dose dependent changes in cognitive performance following acute administration of a Ginkgo biloba/Panax ginseng combination to healthy young volunteers. Nutritional Neuroscience, 4:399-412


Kennedy DO, Scholey AB and Wesnes K (2001) Dose dependent changes in cognitive performance and mood following acute administration of Ginseng to healthy young volunteers. Nutritional Neuroscience 4:295-310


Kennedy DO, Scholey AB, Wesnes K (2000) The dose dependent cognitive effects of acute administration of Ginkgo biloba to healthy young volunteers. Psychopharmacology 151:416-423


Resveratrol

Wightman EL, Eschle T & Kennedy DO (2019). The Cognitive Effects of the Polyphenol Resveratrol in Young, Healthy Humans: A Review of Six Balanced Crossover, Placebo Controlled, Double Blind Trials. International Journal of Nutritional Health & Food Safety, 1(2).pp. 1-9.


Eschle T, Goodall S, Kennedy D & Wightman EL (2020). Acute Resveratrol Administration Increases Neural Effort but Not Whole Body Metabolism or Cognitive Performance in Healthy, Young Participants. Journal of Cognitive Enhancement, pp 1-8. doi.org/10.1007/s41465-019-00139-2.


Wightman EL, Haskell-Ramsay CF, Reay JL, Williamson G, Dew T, Zhang W, Kennedy DO (2015) The effects of chronic trans-resveratrol supplementation on aspects of cognitive function, mood, sleep, health and cerebral blood flow in healthy, young humans. Br J Nutr. 114(9):1427-37


Wightman EL,Reay JL,Haskell CF,Williamson G, Dew TP, Kennedy DO (2014) Effects of resveratrol alone or in combination with piperine on cerebral blood flow parameters and cognitive performance in humans: a randomised, double-blind, placebo-controlled, crossover investigation. British Journal of Nutrition 112(2), 203-213


Kennedy DO, Wightman EL, Reay JL, Lietz G, Okello EJ, Wilde A, Haskell CF (2010) Effects of resveratrol on cerebral blood flow parameters and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation. American Journal of Clinical Nutrition 91:1590-7


Fish Oils

Patan, M. J., Kennedy, D. O., Husberg, C., Hustvedt, S. O., Calder, P. C., Khan, J., … & Jackson, P. A. (2021). Supplementation with oil rich in eicosapentaenoic acid, but not in docosahexaenoic acid, improves global cognitive function in healthy, young adults: results from randomized controlled trials. The American journal of clinical nutrition, 114(3), 914-924.


Jackson, P. A., Husberg, C., Hustvedt, S. O., Calder, P. C., Khan, J., Avery, H., … & Kennedy, D. O. (2020). Diurnal rhythm of plasma EPA and DHA in healthy adults. Prostaglandins, Leukotrienes and Essential Fatty Acids, 154, 102054.


Stonehouse W, Conlon CA, Podd J, Hill SR, Minihane AM, Haskell C, Kennedy D (2013) DHA supplementation improved both memory and reaction time in healthy young adults: a randomized controlled trial. The American Journal of Clinical Nutrition 97: 1134-43


Jackson PA, Deary ME, Reay JL, Scholey AB & Kennedy DO (2012) No effect of 12 weeks’ supplementation with 1 g DHA-rich or EPA-rich fish oil on cognitive function or mood in healthy young adults aged 18-35 years. British Journal of Nutrition 107 (8): 1232-1243


Jackson PA, Reay JL, Scholey AB & Kennedy DO. Docosahexaenoic acid oil modulates the cerebral haemodynamic response to cognitive tasks in healthy young adults: A Near Infrared Spectroscopy pilot study. British Journal of Nutrition 107 (8): 1093-1098


Jackson PA, Reay JL, Scholey AB & Kennedy DO (2012) DHA-rich fish oil modulates the cerebral hemodynamic response to cognitive tasks in healthy young adults. Biological Psychology 89 (1): 183-190


Kennedy DO, Jackson PA, Elliott JM, Scholey AB, Robertson BC, Greer J, Tiplady B, Buchanan T, Haskell CF (2009) Cognitive and mood effects of 8 weeks’ supplementation with 400 mg or 1000 mg of the omega-3 essential fatty acid docosahexaenoic acid (DHA) in healthy children aged 10-12 years. Nutritional Neuroscience 12:48-56


Caffeine

Dodd FL, Kennedy DO, Riby LM, Haskell-Ramsay CF (2015) A double-blind, placebo-controlled study evaluating the effects of caffeine and L-theanine both alone and in combination on cerebral blood flow, cognition and mood. Psychopharmacology 232(14): 2563-76


Haskell CF, Dodd FL, Wightman EL, Kennedy DO (2013) Behavioural effects of compounds co-consumed in dietary forms of caffeinated plants. Nutrition Research Reviews 26: 49-70


Kennedy DO and Haskell CF (2011) Cerebral blood flow and behavioural effects of caffeine in habitual and non-habitual consumers of caffeine: A Near Infrared Spectroscopy study. Biological Psychology 86:298-306


Haskell CF, Kennedy DO, Milne AL, Wesnes KA, Scholey AB (2008) The effects of l-theanine, caffeine and their combination on cognition and mood. Biological Psychology 77:113-22


Scholey AB and Haskell CF (2008) Neurocognitive effects of guarana [invited review]. Drugs of the Future 33:869-874


Kennedy DO, Haskell CF, Robertson B, Reay J, Brewster-Maund C, Luedemann J, Maggini S, Ruf M, Zangara A, Scholey AB (2008) Improved cognitive performance and mental fatigue following a multi-vitamin and mineral supplement with added guarana (Paullinia cupana). Appetite 50:506-13


Haskell CF, Kennedy DO, Wesnes KA, Milne AL, Scholey AB (2007) A double-blind, placebo-controlled, multi-dose evaluation of the acute behavioural effects of guarana in humans. Journal of Psychopharmacology 21: 65-70


Haskell CF, Kennedy DO, Wesnes KA, Scholey AB (2005) Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine. Psychopharmacology 179:813-25


Kennedy DO, Haskell CF, Wesnes KA, Scholey AB (2004) Improved cognitive performance in human volunteers following administration of guarana (Paullinia cupana) extract: comparison and interaction with Panax ginseng. Pharmacology, Biochemistry & Behavior 79(3):401-11


Kennedy DO and Scholey AB (2004) A glucose-caffeine ‘energy drink’ ameliorates subjective and performance deficits during prolonged cognitive demand. Appetite 42:331-333


Scholey AB and Kennedy DO (2004) Cognitive and physiological effects of an “energy drink”: an evaluation of the whole drink and of glucose, caffeine and herbal flavouring fractions. Psychopharmacology 176:320-330


Mackay M, Tiplady B & Scholey AB (2002) Interactions between alcohol and caffeine in relation to psychomotor speed and accuracy. Human Psychopharmacology- Clinical and Experimental, 17: 151-156

Dark Chocolate Blocks

Cocoa Polyphenols

Keane KM, Haskell-Ramsay CF, Veasey RC, Howatson G (2016) Montmorency Tart cherries (Prunus cerasus L.) modulate vascular function acutely, in the absence of improvement in cognitive performance. Br J Nutr. 116: 1935-1944


Watson AW, Haskell-Ramsay CF, Kennedy DO, Cooney JM, Trower T, Scheepens A (2015) Acute supplementation with blackcurrant extracts modulates cognitive functioning and inhibits monoamine oxidase-B in healthy young adults. Journal of Functional Foods, 17: 524-539


Haskell CF, Watson AW (2013) Cocoa, blood flow and the brain. In Skinner M (Ed) Bioactives in Fruit: Health Properties and Functional Foods. Wiley Press, pp 367-388


Scholey A, French S, Morris P, Kennedy D, Milne A, Haskell C (2010) Consumption of cocoa flavanols results in acute improvements in mood and cognitive performance during sustained mental effort. Journal of Psychopharmacology 24:1505-14


Exercise and appetite

Veasey RC, Haskell-Ramsay CF, Kennedy DO, Tiplady B, Stevenson EJ (2015) The effect of breakfast prior to morning exercise on cognitive performance, mood and appetite later in the day in habitually active women. Nutrients, 14;7(7): 5712-32


Veasey RC, Haskell-Ramsay CF, Kennedy DO, Wishart K, Maggini S, Fuchs CJ, Stevenson EJ (2015) The effects of supplementation with a vitamin and mineral complex with guarana prior to fasted exercise on affect, exertion, cognitive performance, and substrate metabolism: A randomized controlled trial. Nutrients, 7(8): 6109-27


Thompson KG, Turner L, Prichard J, Dodd F, Kennedy DO, Haskell C, Blackwell JR, Jones AM (2014) Influence of dietary nitrate supplementation on physiological and cognitive responses to incremental cycle exercise. Respir Physiol Neurobiol. 193:11-20


Veasey RC, Gonzalez JT, Kennedy DO, Haskell CF, Stevenson EJ (2013) Breakfast consumption and exercise interact to affect cognitive performance and mood later in the day: a randomized controlled trial. Appetite 68:38-44


Gonzalez, J.T., Veasey, R.C., Rumbold, P.L, & Stevenson, E.J. (2012). Breakfast and Exercise Contingently Affect Postprandial Metabolism and Energy Balance in Physically Active Males. British Journal of Nutrition. 23:1-12


Gonzalez JT, Veasey RC, Rumbold PLS, Stevenson EJ. (2012) Consistency of metabolic responses and appetite sensations under postabsorptive and postprandial conditions. Appetite. 59 (2): 228-233


Gonzalez JT, Veasey RC, Stevenson EJ. (2011) Collective effects of breakfast consumption and exercise on subsequent postprandial metabolism, appetite and energy balance. Proceedings of the Nutrition Society, 70 (OCE6), E378

Person Holding Barbell

Miscellaneous

Assorted Sliced Fruits

Babateen, A. M., Shannon, O. M., O’Brien, G. M., Okello, E., Smith, E.,Christina Koehl, C., Fostier, W., Wightman, E., Kennedy, D., Mathers, J.C., & Siervo, M. (2022). Incremental Doses of Nitrate-Rich Beetroot Juice Do Not Modify Cognitive Function and Cerebral Blood Flow in Overweight and Obese Older Adults: A 13-Week Pilot Randomised Clinical Trial. Nutrients, 14(5), 1052.


Jackson, P. A., Haskell-Ramsay, C., Forster, J., Khan, J., Veasey, R., Kennedy, D. O., & Wightman, E. L (2021). Acute cognitive performance and mood effects of coffee berry and apple extracts: A randomised, double blind, placebo controlled crossover study in healthy humans. Nutritional Neuroscience, 1-9.


Babateen AM, Shannon OM, O’Brien GM, Okello E, Khan AA, Rubele S, Wightman E, Smith E, McMahon N, Olgacer D, Koehl C, Fostier W, Mendes I, Kennedy D, Mathers JC, Siervo M. (2021). Acceptability and Feasibility of a 13-Week Pilot Randomised Controlled Trial Testing the Effects of Incremental Doses of Beetroot Juice in Overweight and Obese Older Adults. Nutrients, 26;13(3):769.


Wightman EL, Jackson PA, Forster J, Khan J, Wiebe JC, Gericke N & Kennedy DO (2020). Acute Effects of a Polyphenol-Rich Leaf Extract of Mangifera indica L. (Zynamite) on Cognitive Function in Healthy Adults: A Double-Blind, Placebo-Controlled Crossover Study. Nutrients, 12(8), 2194.


Jackson PA, Wightman EL, Veasey R, Forster J, Khan J, Saunders C, Mitchell S, . Haskell-Ramsay CF & Kennedy DO (2020). A Randomized, Crossover Study of the Acute Cognitive and Cerebral Blood Flow Effects of Phenolic, Nitrate and Botanical Beverages in Young, Healthy Humans. Nutrients, 12(8).


Wightman EL, Jackson PA, Khan J, Forster J, Heiner F, Feistel B, Suarez CG, Pischel I & Kennedy DO (2018). The Acute and Chronic Cognitive and Cerebral Blood Flow Effects of a Sideritis scardica (Greek Mountain Tea) Extract: A Double Blind, Randomized, Placebo Controlled, Parallel Groups Study in Healthy Humans. Nutrients, 10 (8), 955.


Kennedy DO, Wightman EL, Forster J, Khan J, Haskell-Ramsay CF & Jackson PA (2017) Cognitive and Mood Effects of a Nutrient Enriched Breakfast Bar in Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled, Parallel Groups Study. Nutrients, 9 (12) 1332


Kennedy DO, Jackson PA, Forster J, Khan J, Grothe T, Perrinjaquet-Moccetti T, Haskell-Ramsay CF (2017) Acute effects of a wild green-oat (Avena sativa) extract on cognitive function in middle-aged adults: A double-blind, placebo-controlled, within-subjects trial. Nutr Neurosci 20: 135-151


Wightman EL, Haskell-Ramsay CF, Thompson KG, Blackwell JR, Winyard PG, Forster J, Jones AM, Kennedy DO (2015) Dietary nitrate modulates cerebral blood flow parameters and cognitive performance in humans: A double-blind, placebo-controlled, crossover investigation. Physiology & Behavior, 149: 149-158



Kennedy DO (2014) Plants and the Human Brain. Oxford University Press, New York


Kennedy, David O. Polyphenols and the Human Brain: Plant Secondary Metabolites: Ecologic Roles and Endogenous Signaling Functions Drive Benefits. Advances in Nutrition: An International Review Journal 5.5 (2014): 515-533.


Kennedy DO (2013) Reply to MP Pase and C Stough. American Journal of Clinical Nutrition 98: 510-511


Jackson, PA & Kennedy, DO (2013) The application of near infrared spectroscopy in nutritional intervention studies. Frontiers in Human Neuroscience 7:473


Wightman EL, Haskell CF, Forster JS, Veasey RC, & Kennedy DO (2012) Epigallocatechin gallate (EGCG), cerebral blood flow parameters, cognitive performance and mood in healthy humans: a double-blind, placebo-controlled, crossover investigation. Human Psychopharmacology 27:177-86


Wightman, E.L & Kennedy, D.O. (2012). Polyphenol modulation of blood flow and oxygenation. In: R Watson (Ed) Polyphenols in Human Health and Disease. Elsevier


Scholey AB, Macpherson H, Sunram-Lea S, Elliott JM, Stough C, Kennedy DO (2012) Glucose enhancement of recognition memory: Differential effects on effortful processing but not aspects of ‘remember-know’ responses. Neuropharmacology 64: 544-549


Sizonenko S, Babiloni C, de Bruin EA,. lsaacs EB, Jonsson LS, Kennedy DO, Hasan Mohajen M, Moreines J, Pietrini P, Walhovd KB, Winwood RJ, Sijben JW (2013) Brain imaging and human nutrition: Which measures to use in intervention studies? British Journal of Nutrition 110; S1-S30


Kennedy DO and Wightman EL (2011) Herbal extracts and phytochemicals: plant secondary metabolites and the enhancement of human brain function. Advances in Nutrition 2:32-50


Kennedy DO, Wightman E, Okello EJ (2009) Medicinal plants, phytochemicals and Alzheimer’s Disease. In: A Martinez (Ed) Emerging Drugs and Targets for Alzheimer’s Disease. Royal Chemistry Society


Scholey AB, Haskell CF, Robertson B, Kennedy DO, Milne A, Wetherell M (2009) Chewing gum alleviates negative mood and reduces cortisol during acute laboratory psychological stress. Physiology and Behavior 97:304-12


Scholey AB, Sunram-Lea S, Greer J, Elliot J, Kennedy DO (2009) Glucose administration prior to a divided attention task improves tracking performance but not word recognition: evidence against differential memory enhancement? Psychopharmacology 202:549-558


Scholey AB, Sunram-Lea SI, Greer J, Elliott J, Kennedy DO (2009) Glucose enhancement of memory depends on initial thirst. Appetite 53(3):426-9


Scholey AB, Parrott A, Kennedy DO (2007) Psychotropic Medicine. In Cambridge Handbook of Psychology, Health & Medicine (Ed. Ayers S) 685-687


Ingwersen J, Defeyter G, Kennedy DO, Wesnes K, Scholey AB (2007) A low glycaemic index breakfast cereal preferentially prevents children’s cognitive performance from declining throughout the morning. Appetite 49(1):240-244


Scholey AB, Laing S, Kennedy DO (2006) Blood glucose changes and memory: effects of manipulating emotionality and mental effort. Biological Psychology 71:12-19


Wesnes KA, Zangara A, Scholey AB, Kennedy DO (2004) Natural products as cognition enhancing agents. In Buccafusco JJ (Ed.) Cognitive Enhancing Drugs. (pp.151-178). Basel-Boston-Berlin, Birkhauser Verlag


Scholey AB, Harper S, Kennedy DO (2001) Cognitive demand and blood glucose. Physiology and Behavior 73:585-592


Neave N, Scholey AB, Emmett JR, Moss M, Kennedy DO, Wesnes K (2001) Water ingestion improves subjective alertness, but has no effect on cognitive performance in dehydrated healthy young volunteers. Appetite, 37: 255-256


Kennedy DO and Scholey AB (2000) Glucose administration, heart rate and cognitive performance: effects of increasing mental effort. Psychopharmacology 149:63-71


Research collaborators and funders

Contact Us

The Brain, Performance & Nutrition Research Centre

Northumberland Building

Northumbria University

Newcastle upon Tyne, NE1 8ST, United Kingdom





(+44) 0191 243 7257

bpnrc@northumbria.ac.uk


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